Concepedia

Synthesis of 4-thiophen-2′-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel

Francesca Cateni, Marina Zacchigna, Nicoletta Pedemonte, Luis J. V. Galietta, Marco T. Mazzei, Paola Fossa, Michele Giampieri, Mauro Mazzei, Mauro Mazzei

Bioorganic & Medicinal Chemistry · 2009 · 24 citations · 17 references

DOI

Concepts

References

17

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Gerene M. Denning, Matthew P. Anderson, Jane F. Amara et al. · Nature · 1992 · 1.2K citations

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Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Wilfried Dalemans, Pascal Barbry, Guy Champigny et al. · Nature · 1991 · 700 citations

, , +13

Small-molecule correctors of defective  F508-CFTR cellular processing identified by high-throughput screening

Nicoletta Pedemonte · Journal of Clinical Investigation · 2005 · 534 citations · Full text

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Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.

J. Hescheler, R. Meyer, S. Plant et al. · Circulation Research · 1991 · 524 citations · Full text

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Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

Fredrick Van Goor, Kimberly Straley, Dong Cao et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 502 citations

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