ω‐Dialkylaminoalkyl ethers of phenyl‐(5‐substituted 1‐phenyl‐1<i>H</i>‐pyrazol‐4‐yl)methanols with analgesic and anti‐inflammatory activity

Giulia Menozzi, Luisa Mosti, Paola Fossa, +2

Journal of Heterocyclic Chemistry

Pharmaceutical ScienceOrganic ChemistryChemistryHeterocycle ChemistryExperimental Pharmacology +15

Pyrazolo[3,4-<i>d</i>]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation

Fabio Carraro, Antonella Naldini, Annalisa Pucci, +14

Journal of Medicinal Chemistry

ApoptosisCell DeathCellular PharmacologyCell ProliferationChemical Biology +18

Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles

Giulia Menozzi, Luisa Merello, Paola Fossa, +9

Bioorganic & Medicinal Chemistry

Medicinal ChemistryHeterocyclicNatural SciencesOrganic ChemistryAntimicrobial Activity +5

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation

Silvia Schenone, Olga Bruno, Angelo Ranise, +10

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineNatural SciencesNew PyrazoloA431 Antiproliferative Activity +6

Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line

Silvia Schenone, Olga Bruno, Francesco Bondavalli, +9

European Journal of Medicinal Chemistry

Antiproliferative ActivityMedicinePharmacological AgentAnti-cancer AgentDrug Development +4

HSPB1 and HSPB8 in inherited neuropathies: study of an Italian cohort of dHMN and CMT2 patients

Simona Capponi, Alessandro Geroldi, Paola Fossa, +6

Journal of the Peripheral Nervous System

Hspb8 Exons 1GeneticsPathologyNeurochemical BiomarkersDisease Gene Identification +14

Synthesis and 3D QSAR of New Pyrazolo[3,4-<i>b</i>]pyridines:  Potent and Selective Inhibitors of A₁Adenosine Receptors

Fabrizio Manetti, Silvia Schenone, Francesco Bondavalli, +11

Journal of Medicinal Chemistry

Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1

Simona Capponi, Thomas Geuens, Alessandro Geroldi, +12

Human Mutation

Neurodegenerative DiseasesMolecular ChaperonesAmyotrophic Lateral SclerosisCandidate Gene Hspb1Hspb1 Mutations +12

Insights into the Structure and Pharmacology of the Human Trace Amine‐Associated Receptor 1 (<i>h</i>TAAR1): Homology Modelling and Docking Studies

Elena Cichero, Stefano Espinoza, Raul R. Gainetdinov, +2

Chemical Biology & Drug Design

Drug TargetMolecular BiologyHtaar1 Key ResiduesSynaptic SignalingMolecular Pharmacology +22

Novel angular furo and thieno-quinolinones: synthesis and preliminary photobiological studies

Paola Fossa, Luisa Mosti, Giulia Menozzi, +3

Bioorganic & Medicinal Chemistry

PhotochemistryMechanistic PhotochemistryNovel Angular FuroSynthetic PhotochemistryOrganic Chemistry +1