Concepedia

Identification of the Molecular Mechanisms for Dedifferentiation at the Invasion Front of Colorectal Cancer by a Gene Expression Analysis

Yoshimasa Oku, Takashi Shimoji, Katsunari Takifuji, Tsukasa Hotta, Shozo Yokoyama, Kenji Matsuda, Takashi Higashiguchi, Toshiji Tominaga, Toru Nasu, Koichi Tamura,

Clinical Cancer Research · 2008 · 28 citations · 34 references

DOIFull text

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Abstract

The molecular mechanisms constructed with 8 genes from three networks of transforming growth factor-beta, Wnt, and Hedgehog signals were found to correlate with dedifferentiation at the invasion front of colorectal cancer.

References

34

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

Nucleic Acids Research · 2002 · 3.5K citations · Full text

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A molecular signature of metastasis in primary solid tumors

Sridhar Ramaswamy, Ken N. Ross, Eric S. Lander et al. · Nature Genetics · 2002 · 2.5K citations

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Knowledge-based analysis of microarray gene expression data by using support vector machines

Michael P. Brown, William Noble Grundy, David Lin et al. · Proceedings of the National Academy of Sciences · 2000 · 2.3K citations · Full text

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Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms

Peter A. Hall, David A. Levison, Amanda L. Woods et al. · The Journal of Pathology · 1990 · 1.5K citations

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

David M. Berman, Sunil Karhadkar, Anirban Maitra et al. · Nature · 2003 · 1.3K citations

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