Mechanism of anti-angiogenic activities of chitooligosaccharides may be through inhibiting heparanase activity

Effect of chitosan on epithelial permeability and structure

V. Dodane · International Journal of Pharmaceutics · 1999 · 568 citations

Epithelial Permeability, Polysaccharide, Matrix Biology +3

Heparan Sulfate Degradation: Relation to Tumor Invasive and Metastatic Properties of Mouse B16 Melanoma Sublines

Motowo Nakajima, Tatsuro Irimura, Daniela Ferrante et al. · Science · 1983 · 347 citations

Immunology, Biological Microenvironments, Pathology +21

Control of Angiogenesis with Synthetic Heparin Substitutes

Judah Folkman, Paul B. Weisz, Madeleine M. Joullié et al. · Science · 1989 · 290 citations

Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells

Hyun Joong Yoon, Myoung E. Moon, Haeng Soon Park et al. · Biochemical and Biophysical Research Communications · 2007 · 209 citations

Inflammation, Macrophage Biology, Cytokine +12

Depolymerized products of chitosan as potent inhibitors of tumor-induced angiogenesis

K.V. Harish Prashanth, Rudrapatnam N. Tharanathan · Biochimica et Biophysica Acta (BBA) - General Subjects · 2004 · 179 citations

Angiogenesis, Polymer-drug Conjugate, Medicine +7