Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

Dennis J. Stuehr, Carl Nathan · The Journal of Experimental Medicine · 1989 · 1.8K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Characterization of tumor necrosis factor-deficient mice

Michael W. Marino, Ashley R. Dunn, Dianne Grail et al. · Proceedings of the National Academy of Sciences · 1997 · 793 citations

Life Sciences, Immunology, Pathology +17

Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes

Xiao Hui Zhang, Carsten J. Kirschning, Roberta Mancinelli et al. · Journal of Biological Chemistry · 1999 · 601 citations · Full text

Life Sciences, Immunology, Microbiology +17

Immunological activity of chitin and its derivatives

Keiko Nishimura, S. Nishimura, Nobuyuki Nishi et al. · Vaccine · 1984 · 395 citations

Life Sciences, Biochemistry, Immunology +6

Chitosan-mediated stimulation of macrophage function

Gianfranco Peluso, Orsolina Petillo, Marilena Ranieri et al. · Biomaterials · 1994 · 387 citations

Life Sciences, Cell Biology, Immunology +9