Concepedia

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

Roland Schmitz, Ryan M. Young, Michele Ceribelli, Sameer Jhavar, Wenming Xiao, Meili Zhang, George W. Wright, Arthur L. Shaffer, Daniel J. Hodson, Eric D. Buras,

Nature · 2012 · 915 citations · 42 references

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42

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux et al. · Cell · 2011 · 2.8K citations · Full text

, , +10

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

Cornelis Murre, Patrick Page-McCaw, David Baltimore · Cell · 1989 · 2.7K citations

, , +16

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Simon Forbes, Nidhi Bindal, Sally Bamford et al. · Nucleic Acids Research · 2010 · 2.3K citations · Full text

, , +17

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

J. Alan Diehl, Mangeng Cheng, Martine F. Roussel et al. · Genes & Development · 1998 · 2.1K citations · Full text

, , +17

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

Cornelis Murre, Patrick Page-McCaw, Harald Vaessin et al. · Cell · 1989 · 1.9K citations

, , +12