From Agonist To Antagonist: Fab Fragments of an Agonist-Like Monoclonal Anti-β₂-Adrenoceptor Antibody Behave as Antagonists

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation

Terence E. Hébert, Serge Moffett, Jean-Pierre Morello et al. · Journal of Biological Chemistry · 1996 · 768 citations · Full text

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Brian K. Kobilka, Richard A. F. Dixon, Thomas Frielle et al. · Proceedings of the National Academy of Sciences · 1987 · 682 citations · Full text

Beta 2-Adrenergic Receptor, Cellular Physiology, Molecular Pharmacology +17

Coupling of β₂-Adrenoceptor to G_iProteins and Its Physiological Relevance in Murine Cardiac Myocytes

Rui-Ping Xiao, Ying-Ying Zhou, Heping Cheng et al. · Circulation Research · 1999 · 386 citations