Concepedia

Thrombomodulin Gene Mutations Associated With Myocardial Infarction

Helen Ireland, G Kunz, Konstantinos Kyriakoulis, Peter Stubbs, David A. Lane

Circulation · 1997 · 135 citations · 15 references

DOI

Abstract

The findings suggest that mutations in the promoter region of the thrombomodulin gene may constitute a risk for arterial thrombosis.

References

15

The Regulation of Natural Anticoagulant Pathways

Charles T. Esmon · Science · 1987 · 698 citations

The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions

Val C. Sheffield, John S. Beck, Anne E. Kwitek et al. · Genomics · 1993 · 675 citations

, , +10

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

Charles T. Esmon, N L Esmon, K. Harris · Journal of Biological Chemistry · 1982 · 433 citations · Full text

, , +17

Thrombomodulin blocks the ability of thrombin to activate platelets.

N L Esmon, R C Carroll, Charles T. Esmon · Journal of Biological Chemistry · 1983 · 219 citations · Full text

, , +17

Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control.

Robert W. Jackman, David Beeler, Linda M.S. Fritze et al. · Proceedings of the National Academy of Sciences · 1987 · 126 citations · Full text

, , +20