Concepedia

Inhibition of PI3K by PX-866 Prevents Transforming Growth Factor-α–Induced Pulmonary Fibrosis

Timothy D. Le Cras, Thomas R. Korfhagen, Cynthia Davidson, Stephanie Schmidt, Matthew Fenchel, Machiko Ikegami, Jeffrey A. Whitsett, William D. Hardie

American Journal Of Pathology · 2009 · 62 citations · 31 references

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31

An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon, Jennifer L. Slack, P. Linga Reddy et al. · Science · 1998 · 1.6K citations

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Jeffrey A. Engelman, Liang Chen, Xiaohong Tan et al. · Nature Medicine · 2008 · 1.3K citations · Full text

, , +17

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

Amir Abdollahi, Minglun Li, Ping Gong et al. · The Journal of Experimental Medicine · 2005 · 384 citations · Full text

, , +17

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

Paola D. Vermeer, Lisa A. Einwalter, Thomas O. Moninger et al. · Nature · 2003 · 363 citations

, , +8

Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung

Jay W. Tichelaar, Wei Lu, Jeffrey A. Whitsett · Journal of Biological Chemistry · 2000 · 322 citations · Full text

, , +13