Gut · 1965 · 380 citations · 12 references
Life SciencesBiochemistryClinical BiochemistryEnzymologyProtein BiochemistryEnzyme KineticsEnzyme StabilityPh AnalysisEnzyme Ph StabilityPh DependencePh Dependence Of Enzyme ActivityPh Effects On Enzyme ActivityPh Effects On EnzymesPh Effects On StabilityPh StabilityPh-dependent Stability
A study of the effect ofpH on the stability and activity of pepsin showed that 70 % of maximal peptic activity was still present at pH 4 5 and that pepsin was irreversibly inacti- vated at pH 8. The clinical implications of these findings are discussed.
12