Combined effect of 25‐<scp>OH</scp> vitamin D plasma levels and genetic <scp><scp>V</scp></scp><i>itamin </i><scp><scp>D</scp><scp>R</scp></scp><i>eceptor</i> (<scp><scp>NR 1I1</scp></scp>) variants on fibrosis progression rate in <scp>HCV</scp> patients

Abstract

Low 25-OH vitamin D plasma levels and the unfavourable VDR bAt[CCA]-haplotype are associated with rapid fibrosis progression in chronic HCV patients. In combination, both variables exert significant additive effects on fibrosis progression.