TIS21/BTG2/PC3 is expressed through PKC-δ pathway and inhibits binding of cyclin B1-Cdc2 and its activity, independent of p53 expression

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

Dawn E. Ouelle, Frédérique Zindy, Richard A. Ashmun et al. · Cell · 1995 · 1.5K citations · Full text

Tumor Biology, Medicine, Molecular Biology +8

Database of p53 gene somatic mutations in human tumors and cell lines.

Monica Hollstein, Kevin P. Rice, Marc S. Greenblatt et al. · PubMed · 1994 · 863 citations

Human Tumors, Tumor Biology, Somatic Variant +14

Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation

Masahiro Asada · The EMBO Journal · 1999 · 582 citations · Full text

Apoptosis Inhibitory Activity, Cell Regulation, Apoptosis +7

Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.

Harald Mischak, J.A. Goodnight, Walter Kölch et al. · Journal of Biological Chemistry · 1993 · 545 citations · Full text

Pkc Isozymes, Cell Proliferation, Cell Growth +20

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

Jean-Pierre Rouault, Nicole Falette, Fabienne Guéhenneux et al. · Nature Genetics · 1996 · 431 citations

Tumor Biology, Chromatin, Genome Instability +11