Intratumoral Injection of Dendritic Cells Engineered to Secrete Interleukin-12 by Recombinant Adenovirus in Patients With Metastatic Gastrointestinal Carcinomas - Concepedia

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Intratumoral Injection of Dendritic Cells Engineered to Secrete Interleukin-12 by Recombinant Adenovirus in Patients With Metastatic Gastrointestinal Carcinomas

DOI Full Paper Access

174

Citations

40

References

2004

Year

Guillermo Mazzolini, Carlos Alfaro, Bruno Sangro, Esperanza Feijoó, Juan Ruiz, Alberto Benito, Iñigo Tirapu, Ainhoa Arina, Josu Sola, Maite Herráiz,

Journal of Clinical Oncology

Abstract

Intratumoral injection of DC transfected with an adenovirus encoding interleukin-12 to patients with metastatic gastrointestinal malignancies is feasible and well tolerated. Further studies are necessary to define and increase clinical efficacy.

References

	Year	Citations

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