Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling

THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO‐CALLED INTESTINAL‐TYPE CARCINOMA

P Laurén · Acta Pathologica Microbiologica Scandinavica · 1965 · 6.2K citations

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Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

Medicine, Biochemistry, Molecular Biology +8

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature · 1997 · 1.8K citations

Life Sciences, Molecular Biology, Cell Signaling +8

Targeted disruption of the mouse <i>Stat3</i> gene leads to early embryonic lethality

Kiyoshi Takeda, Koichi Noguchi, Takashi Tanaka et al. · Proceedings of the National Academy of Sciences · 1997 · 1.3K citations

Life Sciences, Developmental Biology, Genetics +15

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

Life Sciences, Immunology, Pathology +17