Concepedia

A short and efficient synthesis of enantiopure (+)-N-Boc-7-azabicyclo[2.2.1]heptan-2-one utilizing an asymmetric desymmetrization protocol: formal total synthesis of (−)-epibatidine

Ganesh Pandey, Shashi Kant Tiwari, Ram Shanker Singh, R. S. MALI

Tetrahedron Letters · 2001 · 28 citations · 25 references

DOI

Concepts

References

25

Protective groups in organic synthesis

Philip Hodge · Polymer · 1992 · 2.2K citations

, , +8

Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

Thomas F. Spande, H. Martin Garraffo, Michael W. Edwards et al. · Journal of the American Chemical Society · 1992 · 564 citations

, , +7

Epibatidine, a potent analgetic and nicotinic agonist.

Barbara Badio, John W. Daly · Molecular Pharmacology · 1994 · 387 citations

, , +12

Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors

Anthony W. Bannon, Michael Decker, Mark W. Holladay et al. · Science · 1998 · 370 citations · Full text

, , +17

Desulfonylation of aryl alkyl sulfones

Barry M. Trost, Henry C. Arndt, Paul E. Strege et al. · Tetrahedron Letters · 1976 · 284 citations

, , +3