Concepedia

Desymmetrization

Desymmetrization is a biocatalytic strategy that belongs to the class of stereoselective transformations, wherein an enzyme selectively modifies a prochiral or meso substrate to yield a single chiral product by differentiating between enantiotopic groups or faces.

587

Publications

26.5K

Citations

2K

Authors

463

Institutions

Publications per year

2017–2026

185

Parents

Publications

587

Enantioselective desymmetrisation

Michael C. Willis · Journal of the Chemical Society Perkin Transactions 1 · 1999 · 328 citations

, , +6

Peptide-Based Catalysts Reach the Outer Sphere through Remote Desymmetrization and Atroposelectivity

Anthony J. Metrano, Scott J. Miller · Accounts of Chemical Research · 2018 · 289 citations · Full text

, , +16

Enantioselective electrochemical cobalt-catalyzed aryl C–H activation reactions

Tristan von Münchow, Suman Dana, Yang Xu et al. · Science · 2023 · 276 citations

, , +17

Enantioselective Synthesis of α,α-Disubstituted Cyclopentenes by an <i>N</i>-Heterocyclic Carbene-Catalyzed Desymmetrization of 1,3-Diketones

Manabu Wadamoto, Eric M. Phillips, Troy E. Reynolds et al. · Journal of the American Chemical Society · 2007 · 254 citations · Full text

, , +13

Copper-Catalyzed Diastereo- and Enantioselective Desymmetrization of Cyclopropenes: Synthesis of Cyclopropylboronates

Alejandro Parra, Laura Amenós, Manuel Guisán‐Ceinos et al. · Journal of the American Chemical Society · 2014 · 238 citations · Full text

, , +8

1–5 of 587

Authors

2K

  1. TT
    Tetsuaki Tanaka

    The University of Osaka, Japan

    8 publications · 186 citations

    8

    h-index

  2. CI
    C. IWATA

    The University of Osaka, Japan

    8 publications · 186 citations

    8

    h-index

  3. NM
    Naoyoshi Maezaki

    The University of Osaka, Japan

    8 publications · 186 citations

    8

    h-index

  4. WZ
    Wanbin Zhang

    Shanghai Jiao Tong University, China

    7 publications · 228 citations

    7

    h-index

  5. QC
    Qian Cai

    Chinese Academy of Sciences, China

    7 publications · 294 citations

    7

    h-index

1–5 of 2K

Institutions

463

  1. Chinese Academy of Sciences

    Beijing, China

    27 h-index

    105 publications

    5.9K citations

  2. Shanghai Institute of Organic Chemistry

    Shanghai, China

    20 h-index

    50 publications

    2.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    91 publications

    3.3K citations

  4. Indian Institute of Chemical Technology

    Hyderabad, India

    14 h-index

    55 publications

    1.4K citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    14 h-index

    37 publications

    1.9K citations

  6. The University of Osaka

    Osaka, Japan

    13 h-index

    68 publications

    1.5K citations

  7. Nankai University

    Tianjin, China

    12 h-index

    26 publications

    1.6K citations

  8. Shanghai Jiao Tong University

    Shanghai, China

    11 h-index

    59 publications

    2.3K citations

1–8 of 463

Venues

  1. Angewandte Chemie International Edition

    58 publications · 3.8K citations

    40

    h-index

  2. Journal of the American Chemical Society

    JACS · 51 publications · 4K citations

    37

    h-index

  3. Organic Letters

    OL · 71 publications · 2.8K citations

    34

    h-index

  4. The Journal of Organic Chemistry

    JOC · 53 publications · 2.6K citations

    33

    h-index

  5. Chemistry - A European Journal

    28 publications · 1.1K citations

    22

    h-index

1–5