Concepedia

Restoration of IRF1-dependent anticancer effects by MEK inhibition in human cancer cells

Nader AbuSara, Seyd Razavi, Leena Derwish, Yumiko Komatsu, María Licursi, Kensuke Hirasawa

Cancer Letters · 2014 · 28 citations · 43 references

DOI

Concepts

References

43

Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

Dennis J. Slamon, Brian Leyland‐Jones, Steven Shak et al. · New England Journal of Medicine · 2001 · 11.5K citations · Full text

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Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer

Charles E. Geyer, John Forster, Deborah Lindquist et al. · New England Journal of Medicine · 2006 · 3.5K citations · Full text

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p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1α (HIF-1α) and Enhance the Transcriptional Activity of HIF-1

Darren E. Richard, Edurne Berra, Emmanuel Gothié et al. · Journal of Biological Chemistry · 1999 · 784 citations · Full text

, , +13

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1

Nobuyuki Tanaka, Masahiko Ishihara, Motoo Kitagawa et al. · Cell · 1994 · 494 citations

, , +13

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK

Lindsey Allan, Nick Morrice, Suzanne C. Brady et al. · Nature Cell Biology · 2003 · 471 citations

, , +12