The Third Transmembrane Helix of the Cannabinoid Receptor Plays a Role in the Selectivity of Aminoalkylindoles for CB2, Peripheral Cannabinoid Receptor

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5.1K citations

Medicine, Molecular Biology, Pharmacology +14

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

Lisa A. Matsuda, Stephen J. Lolait, Michael Brownstein et al. · Nature · 1990 · 5K citations

Life Sciences, Molecular Biology, Pharmacology +11

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

Murielle Rinaldi‐Carmona, Francis Barth, Michel Héaulme et al. · FEBS Letters · 1994 · 1.8K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

Christian C. Felder, Kelly E. Joyce, Eileen M. Briley et al. · Molecular Pharmacology · 1995 · 879 citations

Medicine, Pharmacology, Cell Signaling +7