Microcontact Printing of Proteins

Abstract

The direct patterning of biomolecules on a solid substrate can be achieved using microcontact printing, a method that has been very successfully adopted for the precise and gentle transfer of proteins and lipid bilayers from stamp to substrate in 1 s, without loss of biological activity. The image shown was produced by patterning 16 different proteins onto the polystyrene surface of a cell culture dish using a stamp inked by means of a microfluidic network.