Concepedia

Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel

Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Dafang Zhong

Drug Metabolism and Disposition · 2015 · 31 citations · 21 references

References

21

Clopidogrel for Coronary Stenting

Paul A. Gurbel, Kevin P. Bliden, Bonnie L. Hiatt et al. · Circulation · 2003 · 1.5K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

Alan R. Shuldiner · JAMA · 2009 · 1.5K citations · Full text

Medicine, Cardiology, Pharmacology +17

SpecDis: Quantifying the Comparison of Calculated and Experimental Electronic Circular Dichroism Spectra

Torsten Bruhn, Anu Schaumlöffel, Yasmin Hemberger et al. · Chirality · 2013 · 1.4K citations

Natural Sciences, Chemistry, Physics +15

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Miho Kazui, Yumi Nishiya, Tomoko Ishizuka et al. · Drug Metabolism and Disposition · 2009 · 821 citations

Medicine, Biochemistry, Pharmacology +17

Identification and Biological Activity of the Active Metabolite of Clopidogrel

Pierre Savi, Jean‐Marie Pereillo, Marie-Françoise Uzabiaga et al. · Thrombosis and Haemostasis · 2000 · 748 citations

Medicine, Medicinal Chemistry, Pharmacology +17