Concepedia

A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial

Michael Boyle, Scott C. Bell, Michael W. Konstan, Susanna A. McColley, Steven M. Rowe, Ernst Rietschel, Xiaohong Huang, David Waltz, Naimish Patel, David M. Rodman

The Lancet Respiratory Medicine · 2014 · 442 citations · 17 references

DOI

Concepts

References

17

A CFTR Potentiator in Patients with Cystic Fibrosis and the <i>G551D</i> Mutation

Bonnie W. Ramsey, Jane C. Davies, Noel G. McElvaney et al. · New England Journal of Medicine · 2011 · 2.2K citations · Full text

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Changes in the normal maximal expiratory flow-volume curve with growth and aging.

Ronald J. Knudson, M D Lebowitz, Catharine J. Holberg et al. · PubMed · 1983 · 1.9K citations

, , +17

Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis

Henry J. Fuchs, Drucy Borowitz, David Høyrup Christiansen et al. · New England Journal of Medicine · 1994 · 1.5K citations · Full text

, , +14

Cystic Fibrosis

Steven M. Rowe, Stacey Miller, Eric J. Sorscher · New England Journal of Medicine · 2005 · 1.4K citations

, , +13

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2009 · 1.2K citations · Full text

, , +17