Ernst Rietschel

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

Miriam F. Moffatt, Michael Kabesch, Liming Liang et al. · Nature · 2007 · 1.6K citations

Life Sciences, Genetics, Molecular Genetics +7

Synthetic and natural <i>Escherichia coli</i> free lipid A express identical endotoxic activities

Chris Galanos, O. Lüderitz, Ernst Rietschel et al. · European Journal of Biochemistry · 1985 · 488 citations · Full text

Life Sciences, Biochemistry, Toxicology +10

A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial

Michael Boyle, Scott C. Bell, Michael W. Konstan et al. · The Lancet Respiratory Medicine · 2014 · 442 citations

Pharmacy, Molecular Genetics, Pharmacotherapy +11

Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial

Eitan Kerem, Michael W. Konstan, K. De Boeck et al. · The Lancet Respiratory Medicine · 2014 · 335 citations · Full text

Medicine, Molecular Medicine, Pharmacotherapy +9

Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion

Andra B. Schromm, Klaus Brandenburg, Harald Loppnow et al. · European Journal of Biochemistry · 2000 · 319 citations · Full text

Life Sciences, Immunology, Microbiology +17