Desvenlafaxine Succinate: A New Serotonin and Norepinephrine Reuptake Inhibitor

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

Tadeusz Pacholczyk, Randy Blakely, Susan Amara · Nature · 1991 · 932 citations

Life Sciences, Neurobiology, Neuroscience +14

Duloxetine vs. placebo in patients with painful diabetic neuropathy

D. Goldstein, Yili Lu, Michael J. Detke et al. · Pain · 2005 · 847 citations

Medicine, Pharmacology, Pharmacotherapy +17

Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors

Frank P. Bymaster · Neuropsychopharmacology · 2001 · 720 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Neurotransmitter Receptor and Transporter Binding Profile of Antidepressants and Their Metabolites

Michael J. Owens, W. Neal Morgan, Susan J. Plott et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 671 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17