Prediction of adipose tissue: Plasma partition coefficients for structurally unrelated drugs

A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 423 citations

Pharmacy, Pharmacokinetics, Pharmacology +8

Lipid Solubility and Drug Penetration of the Blood Brain Barrier

William H. Oldendorf · Experimental Biology and Medicine · 1974 · 375 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

A Novel Method for Measuring Membrane-Water Partition Coefficients of Hydrophobic Organic Chemicals: Comparison with 1-Octanol–Water Partitioning

Frank A. P. C. Gobas, Jean M. Lahittete, Gil Garofalo et al. · Journal of Pharmaceutical Sciences · 1988 · 230 citations

Natural Sciences, Chemical Engineering, Chemistry +12

Prediction of the Brain−Blood Distribution of a Large Set of Drugs from Structurally Derived Descriptors Using Partial Least-Squares (PLS) Modeling

Juan M. Luco · Journal of Chemical Information and Computer Sciences · 1999 · 207 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Computation of Brain−Blood Partitioning of Organic Solutes via Free Energy Calculations

Franco Lombardo, James F. Blake, William Curatolo · Journal of Medicinal Chemistry · 1996 · 198 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16