Concepedia

DNA Methylation Profiles and Their Relationship with Cytogenetic Status in Adult Acute Myeloid Leukemia

Sara Álvarez, Javier Suela, Ana Valencia, Agustín F. Fernández, Mark Wunderlich, Xabier Agirre, Felipe Prósper, José I. Martı́n-Subero, Alba Maiqués-Díaz, Francesco Acquadro,

PLoS ONE · 2010 · 81 citations · 31 references

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Abstract

Our study provides a comprehensive epigenetic profiling of AML, identifies new clinical markers for cases with a normal karyotype, and reveals relevant biological information related to the role of fusion proteins on the methylation signature.

References

31

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Epigenetic differences arise during the lifetime of monozygotic twins

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Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

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Comprehensive analysis of CpG islands in human chromosomes 21 and 22

Daiya Takai, Peter A. Jones · Proceedings of the National Academy of Sciences · 2002 · 1.5K citations · Full text

Stepwise Reprogramming of B Cells into Macrophages

Huafeng Xie, Min Ye, Ru Feng et al. · Cell · 2004 · 930 citations · Full text

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