Restoration of Rat Colonic Epithelium After <i>In Situ</i> Intestinal Instillation of the Absorption promoter, Sodium Caprate

Abstract

Design of optimized dosage forms containing C10 should corelease the payload and promoter close to the epithelium in high concentrations. While C10 induces some epithelial damage, its remarkable capacity for epithelial repair may render this effect insignificant in vivo.