Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage - Concepedia

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Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage

65

Citations

37

References

2015

Year

Kenji Yagi, Darcy Lidington, Hoyee Wan, Jessica C. Fares, Manabu Sumiyoshi, Jinglu Ai, Warren D. Foltz, Sergei A. Nedospasov, Stefan Offermanns, Shinji Nagahiro,

Abstract

Vascular smooth muscle cell TNFα and sphingosine-1-phosphate signaling significantly enhance cerebral artery tone in SAH; anti-TNFα and anti-sphingosine-1-phosphate treatment may significantly improve clinical outcome.

References

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