Glycocinnamoylspermidines, a new class of antibiotics. I. Description and fermentation of the organism producing the LL-BM123 antibiotics.

Abstract

The producing organism for the new broad spectrum glycocinnamoylspermidine antibiotics designated LL-BM123beta, gamma1 and gamma2 was characterized as a Nocardia sp. by chemical analysis of the cell wall, growth requirements, morphology and physiological reactions. Fermentation conditions to elaborate and analytical methods to characterize these antibiotics in fermentation filtrates are described.