Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity

Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis

Robert J. Moore, David M. Owens, Gordon Stamp et al. · Nature Medicine · 1999 · 829 citations

Inflammation, Cutaneous Biology, Photocarcinogenesis +10

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

Z Q Wang, B. Auer, Laura Stingl et al. · Genes & Development · 1995 · 777 citations · Full text

Molecular Biology, Cell Death, Cell Proliferation +20

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

Josiane Ménissier de Murcia · The EMBO Journal · 2003 · 623 citations · Full text

Knockout Mouse, Chromatin, Developmental Biology +13

PARP is important for genomic stability but dispensable in apoptosis

Zhao‐Qi Wang, Laura Stingl, Ciaran G. Morrison et al. · Genes & Development · 1997 · 556 citations · Full text

Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention, and Diagnosis

Svetomir N. Markovic, Lori A. Erickson, Ravi D. Rao et al. · Mayo Clinic Proceedings · 2007 · 367 citations

Part 1, Cancer Risk, Cancer Epidemiology +13