Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.

Lucio Tentori, Carlo Leonetti, Marco Scarsella, +8

PubMed

<i>In vitro</i> and <i>In vivo</i> Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016

Andrea Russo, Hyuk‐Chan Kwon, William Burgan, +8

Clinical Cancer Research

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

Lucio Tentori, Pedro Miguel Lacal, Alessia Muzi, +11

European Journal of Cancer

AngiogenesisNatural SciencesPathologyVascular BiologyNeovascularization +3

Pharmacologic Inhibition of Poly(ADP-Ribose) Polymerase Is Neuroprotective Following Traumatic Brain Injury in Rats

Michelle C. LaPlaca, Jie Zhang, Ramesh Raghupathi, +6

Journal of Neurotrauma

Traumatic Brain InjuryPharmacologic InhibitionCell DeathOxidative StressClinical Injury +14

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors

Patricia LoRusso, Jing Li, Angelika M. Burger, +21

Clinical Cancer Research

Are poly(ADP‐ribosyl)ation by PARP‐1 and deacetylation by Sir2 linked?

Jie Zhang

BioEssays

Raman and surface-enhanced Raman spectra of chrysin, apigenin and luteolin

Charlie Corredor, Tatyana Teslova, María Vega Cañamares, +4

Vibrational Spectroscopy

EngineeringSurface ChemistryNatural SciencesSpectroscopySurface Science +5

New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

Viktor R. Drel, Sergey Lupachyk, Hanna Shevalye, +6

Endocrinology

Head and neck cancer radiosensitization by the novel poly(ADP‐ribose) polymerase inhibitor GPI‐15427

Khurram Khan, Koji Araki, Daiyou Wang, +9

Head & Neck

Design and Synthesis of Poly ADP-ribose Polymerase-1 Inhibitors. 2. Biological Evaluation of Aza-5[<i>H</i>]-phenanthridin-6-ones as Potent, Aqueous-Soluble Compounds for the Treatment of Ischemic Injuries

Dana Ferraris, Yao-Sen Ko, Thomas F. Pahutski, +20

Journal of Medicinal Chemistry