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The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis

Signal TransductionSignaling PathwayApoptosisAutophagyCell DeathTumor SuppressorSystems BiologyMedicineCell BiologyCell SignalingTrail-induced Apoptosis