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Relative Lipophilicities, Solubilities, and Structure–Pharmacological Considerations of 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG-CoA) Reductase Inhibitors Pravastatin, Lovastatin, Mevastatin, and Simvastatin

Molecular PharmacologyMedicinal ChemistryReductase Inhibitors PravastatinPharmaceutical ScienceBiochemistryMedicineNatural SciencesStructure–pharmacological ConsiderationsPharmacotherapyLipoprotein MetabolismPharmacologyRelative LipophilicitiesDrug Discovery