Differential Effects of Combined Ad5-Δ24RGD and Radiation Therapy in <i>In vitro</i> versus <i>In vivo</i> Models of Malignant Glioma - Concepedia

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Differential Effects of Combined Ad5-Δ24RGD and Radiation Therapy in <i>In vitro</i> versus <i>In vivo</i> Models of Malignant Glioma

52

Citations

27

References

2007

Year

Martine L.M. Lamfers, Sander Idema, Lisette Bosscher, S. Heukelom, Sharif Moeniralm, Ida H. van der Meulen‐Muileman, Renée M. Overmeer, Paul van der Valk, Victor W. van Beusechem, Winald R. Gerritsen,

Clinical Cancer Research

Abstract

Combined treatment with Ad5-delta 24RGD and irradiation shows enhanced antitumor activity in vitro and in s.c. tumors, but not in an orthotopic glioma model. These differential results underscore the significance of the selected tumor model in assessing the effects of combination therapies with oncolytic adenoviruses.

References

	Year	Citations

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