Concepedia

A Catalytic Asymmetric Vinylogous Mukaiyama Aldol Reaction

Lars V. Heumann, Gary E. Keck

Organic Letters · 2007 · 52 citations · 32 references

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Abstract

A vinylogous Mukaiyama aldol reaction, conducted using 10 mol % of a BITIP catalyst and B(OMe)3 as an additive, effects an enantioselective four-carbon chain extension to give versatile E-alpha,beta-unsaturated thiol esters.

References

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