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COPPER DEFICIENCY IN INFANCY
227
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0
References
1964
Year
MalnutritionNutritionNutrition DevelopmentPublic Health NutritionUndernutritionNutritional InterventionsMaternal NutritionPublic HealthMicronutrient SupplementationSevere AnemiaSupplemental CuClinical NutritionMaternal HealthNutritional ResponseMicronutrientsDevelopmental AnomalyNutritional RequirementInfant NutritionVitamin B12PediatricsChild NutritionNutritional ScienceHuman NutritionMedicine
In four severely malnourished infants who were rehabilitated on high-calorie, low-Cu diets, we have observed the appearance of severe anemia, marked neutropenia, scurvy-like bone changes, and hypocupremia. In 2 cases there was a prompt and dramatic response to Cu supplementation. In the other 2, slower but good responses were obtained with vitamin B12; supplemental Cu produced further responses. The Cu requirement of rapidly growing infants with poor stores is estimated at between 42 and 135 µg/kg/day.