MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man. - Concepedia

Concepedia

Publication | Open Access

MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man.

DOI Full Paper Access

163

Citations

0

References

1993

Year

Kathelijne Peerlinck, Inge De Lepeleire, Michael R. Goldberg, Daniel Farrell, Jeffrey Barrett, Elizabeth Hand, Deborah Panebianco, Hans Deckmyn, Jos Vermylen, Jozef Arnout

Abstract

The results from this study indicate that MK-383 appears to be well tolerated and active in man. It is the first nonpeptide GPIIb/IIIa antagonist that can be used to investigate the antithrombotic potential of this new class of antiplatelet agents.