Double Gold‐Catalysed Annulation of Indoles by Enynones

Abstract

Abstract The gold‐catalysed double functionalisation of indoles is presented. Enynones are used to annulate indoles via a double sodium tetrachloroaurate‐catalysed process involving a mixture of CH activation and alkyne activation modes of promotion. Good yields for the formation of medicinally relevant [6,5,7]‐tricyclic indoles are realised.