Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

Life Sciences, Immunology, Neuroscience +14

B cells regulate autoimmunity by provision of IL-10

Simon Fillatreau, Claire H. Sweenie, Mandy J. McGeachy et al. · Nature Immunology · 2002 · 1.6K citations

Life Sciences, Cell Biology, Immunology +12

Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

E. John Wherry, Joseph N. Blattman, Kaja Murali‐Krishna et al. · Journal of Virology · 2003 · 1.6K citations

Life Sciences, Immunology, Infectious Diseases +17

IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

Yutaka Komiyama, Susumu Nakae, Taizo Matsuki et al. · The Journal of Immunology · 2006 · 1.5K citations · Full text

Life Sciences, Immunology, Pathology +17

Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

Holger Babbe, Axel Roers, Ari Waisman et al. · The Journal of Experimental Medicine · 2000 · 951 citations · Full text

Life Sciences, Immunology, Pathology +17