Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser et al. · Nature · 2003 · 1.5K citations · Full text

Medicine, Cancer Biology, Oncology +12

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

Roberto Pola, Leona Ling, Marcy Silver et al. · Nature Medicine · 2001 · 608 citations

Life Sciences, Cancer Biology, Developmental Biology +13

Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice.

Akira Sasaki, Brendan F. Boyce, Beryl Story et al. · PubMed · 1995 · 422 citations

Medicine, Oncology, Pharmacology +17

Induction of Osteogenic Differentiation by Hedgehog Proteins

Takashi Nakamura, Tomonao Aikawa, Motomi Iwamoto-Enomoto et al. · Biochemical and Biophysical Research Communications · 1997 · 243 citations · Full text

Medicine, Developmental Biology, Genetics +14

Patterns of invasion and routes of tumor entry into the mandible by oral squamous cell carcinoma

James S. Brown, Derek Lowe, Nicholas Kalavrezos et al. · Head & Neck · 2002 · 204 citations · Full text

Dentistry, Oral Pathology, Oral Surgery +17