Concepedia

Diels–Alder Ligation and Surface Immobilization of Proteins

Aline D. de Araujo, José M. Palomo, Janina Cramer, Maja Köhn, Hendrik Schröder, Ron Wacker, Christof M. Niemeyer, Kirill Alexandrov, Herbert Waldmann

Angewandte Chemie International Edition · 2005 · 157 citations · 23 references

DOI

Concepts

Abstract

Mild attachment: Proteins can be ligated chemoselectively and immobilized on functionalized glass surfaces by means of Diels–Alder cycloadditions (see scheme).

References

23

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Cell Surface Engineering by a Modified Staudinger Reaction

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, , +17

Organic reactions in aqueous media

Choice Reviews Online · 1998 · 1.3K citations

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An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms

Oliver Rocks, Anna Peyker, Martin Kahms et al. · Science · 2005 · 853 citations

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Bioconjugate techniques

General Pharmacology The Vascular System · 1997 · 749 citations