Concepedia

Autoproteolysis of PIDD marks the bifurcation between pro‐death caspase‐2 and pro‐survival NF‐κB pathway

Antoine Tinel, Sophie Janssens, Saskia Lippens, Solange Cuenin, Emmanuelle Logette, B Jaccard, Manfredo Quadroni, Jürg Tschopp

The EMBO Journal · 2006 · 168 citations · 31 references

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31

Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

Srinivasa M. Srinivasula, Manzoor Ahmad, Teresa Fernandes‐Alnemri et al. · Molecular Cell · 1998 · 1.1K citations · Full text

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The PIDDosome, a Protein Complex Implicated in Activation of Caspase-2 in Response to Genotoxic Stress

Antoine Tinel, Jürg Tschopp · Science · 2004 · 666 citations

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A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

J.A. Brannigan, Guy Dodson, Helen J. Duggleby et al. · Nature · 1995 · 613 citations

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Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress

Tony T. Huang, Shelly M. Wuerzberger‐Davis, Zhao‐Hui Wu et al. · Cell · 2003 · 552 citations · Full text

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Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain

Jeffery A. Porter, Stephen C. Ekker, Woo-Jin Park et al. · Cell · 1996 · 528 citations · Full text

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