Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1)

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

Long Qt Syndrome, Cardiomyopathy, Genetics +9

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Q. Wang, Mark Curran, Igor Splawski et al. · Nature Genetics · 1996 · 1.8K citations

Cardiac Muscle, Channelopathies, Kvlqt1 Mutations +9

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

Qing Wang, Jiaxiang Shen, Igor Splawski et al. · Cell · 1995 · 1.7K citations · Full text

Long Qt Syndrome, Cardiomyopathy, Genetic Disorder +6

Long QT Syndrome Patients With Mutations of the <i>SCN5A</i> and <i>HERG</i> Genes Have Differential Responses to Na ⁺ Channel Blockade and to Increases in Heart Rate

Peter J. Schwartz, Silvia G. Priori, Emanuela H. Locati et al. · Circulation · 1995 · 812 citations

Mutations in the hminK gene cause long QT syndrome and suppress lKs function

Igor Splawski, Martin Tristani‐Firouzi, Michael H. Lehmann et al. · Nature Genetics · 1997 · 770 citations

Transcriptional Regulation, Signal Transduction, Mendelian Disorder +8