Mutations in the hminK gene cause long QT syndrome and suppress lKs function

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Medicine, Cardiology, Molecular Genetics +16

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Michael C. Sanguinetti, Mark Curran, Anruo Zou et al. · Nature · 1996 · 1.8K citations

Natural Sciences, Biochemistry, Molecular Biology +12

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Q. Wang, Mark Curran, Igor Splawski et al. · Nature Genetics · 1996 · 1.8K citations

Medicine, Genetics, Molecular Genetics +17

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

Jacques Barhanin, Florian Lesage, Eric Guillemare et al. · Nature · 1996 · 1.6K citations

Natural Sciences, Molecular Biology, Physiology +12

A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome

Nathalie Neyroud, Frédérique Tesson, Isabelle Denjoy et al. · Nature Genetics · 1997 · 883 citations

Life Sciences, Genetics, Molecular Genetics +16