Hepatic Pharmacokinetics of Cationic Drugs in a High-Fat Emulsion-Induced Rat Model of Nonalcoholic Steatohepatitis

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Jordi Folch, Marjorie B. Lees, G H S Stanley · Journal of Biological Chemistry · 1957 · 64.9K citations · Full text

Life Sciences, Biochemistry, Bioseparations +11

Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆

Christi A Matteoni, Zobair M. Younossi, T GRAMLICH et al. · Gastroenterology · 1999 · 3.4K citations · Full text

Medicine, Internal Medicine, Pathology +14

Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

K. Sandy Pang, Malcolm Rowland · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 798 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

Martin Weltman, Geoffrey C. Farrell, Pauline de la Μ. Hall et al. · Hepatology · 1998 · 612 citations · Full text

Medicine, Biochemistry, Pathobiology +11

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

MD Weltman, GC Farrell, Chris Liddle · Gastroenterology · 1996 · 395 citations · Full text

Medicine, Biochemistry, Pharmacology +16