Vanadium(III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones

Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents

Karnail S. Atwal, Brian N. Swanson, Steven E. Unger et al. · Journal of Medicinal Chemistry · 1991 · 784 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Novel Alkaloids from the Sponge Batzella sp.: Inhibitors of HIV gp120-Human CD4 Binding

Ashok D. Patil, N. Vasant Kumar, W. C. M. C. Kokke et al. · The Journal of Organic Chemistry · 1995 · 605 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Unprecedented Catalytic Three Component One-Pot Condensation Reaction:  An Efficient Synthesis of 5-Alkoxycarbonyl- 4-aryl-3,4-dihydropyrimidin-2(1H)-ones

Essa Hu, Daniel R. Sidler, Ulf‐H. Dolling · The Journal of Organic Chemistry · 1998 · 501 citations

Natural Sciences, Chemistry, Catalysis +6

A general and expedient method for the solid-phase synthesis of 1,4-benzodiazepine derivatives

Barry A. Bunin, Jonathan A. Ellman · Journal of the American Chemical Society · 1992 · 444 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Dihydropyrimidine calcium channel blockers. II. 3-Substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines

Karnail S. Atwal, George C. Rovnyak, S. David Kimball et al. · Journal of Medicinal Chemistry · 1990 · 378 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8