Novel fatty acid elongases and their use for the reconstitution of docosahexaenoic acid biosynthesis

Basic local alignment search tool

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Bioinformatics, Engineering, Information Retrieval +10

Production of Polyunsaturated Fatty Acids by Polyketide Synthases in Both Prokaryotes and Eukaryotes

James G. Metz, Paul G. Roessler, Daniel Facciotti et al. · Science · 2001 · 763 citations

Bioorganic Chemistry, Pks Enzymes, Engineering +17

ELO2 and ELO3, Homologues of theSaccharomyces cerevisiae ELO1 Gene, Function in Fatty Acid Elongation and Are Required for Sphingolipid Formation

Chan-Seok Oh, David A. Toke, Suzanne Mandala et al. · Journal of Biological Chemistry · 1997 · 479 citations · Full text

Biology, Biosynthesis, Biochemistry +13

Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)?

H Gerster · PubMed · 1998 · 410 citations

Docosahexaenoic Acid, Nutrition, Metabolic Syndrome +13

Identification of a Δ4 Fatty Acid Desaturase fromThraustochytrium sp. Involved in the Biosynthesis of Docosahexanoic Acid by Heterologous Expression inSaccharomyces cerevisiae and Brassica juncea

Xiao Qiu, Haiping Hong, S. L. MacKenzie · Journal of Biological Chemistry · 2001 · 233 citations · Full text