Thyroid Hormone-Responsive SPOT 14 Homolog Promotes Hepatic Lipogenesis, and Its Expression Is Regulated By Liver X Receptor α Through a Sterol Regulatory Element-Binding Protein 1c–Dependent Mechanism in Mice - Concepedia

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Thyroid Hormone-Responsive SPOT 14 Homolog Promotes Hepatic Lipogenesis, and Its Expression Is Regulated By Liver X Receptor α Through a Sterol Regulatory Element-Binding Protein 1c–Dependent Mechanism in Mice

DOI Full Paper Access

81

Citations

32

References

2013

Year

Jing Wu, Chunjiong Wang, Shuo Li, Sha Li, Wanyi Wang, Jing Li, Yujing Chi, Hang Yang, Xiaomu Kong, Yunfeng Zhou,

Abstract

Thrsp is a lipogenic gene in the liver that is induced by the LXR agonist through an LXR-α-mediated, SREBP-1c-dependent mechanism. Therefore, Thrsp may represent a potential therapeutic target for the treatment of NAFLD.

References

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