Journal of Enzyme Inhibition and Medicinal Chemistry · 2009 · 34 citations · 18 references
Life SciencesBotanyPlant BiologyDrug DiscoveryPlant BiochemistryStructure-activity RelationshipsMedicinal PlantsPlant GlycobiologyStructure-activity Relationship AnalysisAntioxidant FractionationBioactive ConstituentsFlavonoid GlycosidesGlycosidase InhibitionMarine GlycosidesPlant Extract AntioxidantsUrease ActivityUrease Inhibitors
Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.
18
Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents
Brian F. Meyer, N. R. Ferrigni, J. E. Putnam et al. · Planta Medica · 1982 · 4.8K citations
Masayuki Yoshikawa, Hiromi Shimada, Norihisa Nishida et al. · Chemical and Pharmaceutical Bulletin · 1998 · 137 citations · Full text