Concepedia

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

Gavin Bendle, Carsten Linnemann, Anna I. Hooijkaas, Laura Bies, Moniek A. de Witte, Annelies Jorritsma, Andrew Kaiser, Nadine Pouw, Reno Debets, Elisa Kieback,

Nature Medicine · 2010 · 436 citations · 36 references

DOI

Concepts

References

36

Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

Richard A. Morgan, Mark E. Dudley, John R. Wunderlich et al. · Science · 2006 · 2.6K citations · Full text

, , +14

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Laura A. Johnson, Richard A. Morgan, Mark E. Dudley et al. · Blood · 2009 · 1.4K citations · Full text

, , +17

TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

Dori A. Thomas, Joan Massagué · Cancer Cell · 2005 · 1.3K citations · Full text

, , +16

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

Luca Gattinoni · Journal of Clinical Investigation · 2005 · 953 citations · Full text

, , +17

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

Willem W. Overwijk, Marc R. Theoret, Steven E. Finkelstein et al. · The Journal of Experimental Medicine · 2003 · 918 citations · Full text

, , +17