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Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of α- and 4-hydroxy metabolites in healthy subjects

Molecular PharmacologySingle Blood SamplePharmacokinetic ModelingHealthy SubjectsPharmacological StudyMedicineParent DrugDrug MonitoringPharmacotherapyPharmacologyPharmacokineticsPharmacodynamic ModelingDrug Analysis